Psellos´s epitaph to "Εἰρήνην καισάρισσαν" alludes to her father as "pégè…nikè" and records his military successes against the Bulgarians names Leon Pegonites as father of Eirene, wife of Ioannes Doukas. The Prosopography of the Byzantine World interprets this passage as indicating Leon Pegonites. Kouroupou and Vannier suggest that it refers to "le patrice Nicétas Pègonitès, stratège de Dyrrachion et vainqueur en 1018 du tsar bulgare Jean Vladislav". A seal dated to before 24 Nov 1059 (when her husband was appointed cæsar by his brother) records "Irène Pègonitissa, magistrissa, vestarchissa et doukaina". Psellos, in his epitaph to "Εἰρήνην καισάρισσαν", records that she refused to bear the insignia of "cæsarissa" after her husband was appointed cæsar because of her serious illness.
The list of obituaries of the monastery of Christ Philanthropos, founded by Empress Eirene Doukas, records the death 8 Sep of "Eirene…agias despoines e kaisárissa". Kouroupou and Vannier suggest that her death "semble [être] antérieure à la naissance de sa petite-fille Irène en 1066". 1