The Alexeiad names "Andronikos, the Cæsar's eldest son" as the father of Empress Eirene. Mikhael Glykas refers to "Iohanni Cæsari…filiis…Constantinus…filius alter…Andronicus".
Co-emperor 1067-1070. Commander of the imperial fleet in 1068, he fled from the battle scene at Manzikert in Aug 1071 and deliberately spread the rumour that the battle was lost, which eventually it was. Protoproedros, protobestiarios. An undated seal records “Andronic Ducas protoproèdre, protovestiaire et domestique des scholes de l’Orient”. Psellos records that "Andronicus, the elder of the cæsar's sons, was given command of the imperial armies". Domestikos of the Orient 1073.
He became a monk as ANTONIOS. Nikeforos Bryennios records that "protovestiarius...Andronicus" died soon after the betrothal of "Comnenum Alexium" to his oldest daughter Eirene. The typikon of Theotokos Kecharitomenes (dated to [1110]) provides for the commemoration 14 Oct of "le...père de ma Majesté, le protoproèdre et grand duc des Scholes d’Orient, kyr Andronic Doukas, qui s’appela...kyr Antoine". The list of obituaries of the monastery of Christ Philanthropos, founded by Empress Eirene Doukas, records the death 14 Oct of "Antoniou monaxou tou patros tes ayias despoines". 1